Toxoplasma gondii and Cryptosporidium parvum lack detectable DNA cytosine methylation.
نویسندگان
چکیده
Epigenetic factors play a role in the expression of virulence traits in Apicomplexa. Apicomplexan genomes encode putative DNA cytosine methylation enzymes. To assess the presence of cytosine methylation of Toxoplasma gondii and Cryptosporidium parvum DNA, we used mass spectrometry analysis and confirmed that these organisms lack detectable methylcytosine in their DNA.
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عنوان ژورنال:
- Eukaryotic cell
دوره 7 3 شماره
صفحات -
تاریخ انتشار 2008